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MARK Los Angeles

MARK Los Angeles
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MARK Los Angeles

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Overview

Date Established 04/2022
Founder Mark Menning
Headquarters None
Industries
Health & Wellness
Science & Research
Beauty
Tech
Website https://www.marklosangeles.com
Social

About

MARK Los Angeles is a skincare company founded by Mark Menning PhD, a pharmaceutical scientist, and Dee Khalsa, a spa and wellness expert. They focus on creating plant-based skincare solutions that are free of harsh chemicals, leveraging Menning's expertise in pharmaceutical precision. Their products are clinically tested, cruelty-free, and designed to provide effective treatment while maintaining high ethical and sustainable standards. The company's mission is to revolutionize skincare through the use of nature's medicinal chemistry.

Founding Story

MARK Los Angeles was founded by pharmaceutical scientist Mark Menning, PhD, whose lifelong interest in flavonoids led him to a breakthrough in skincare science. While flavonoids are well known for their anti-inflammatory and antioxidant benefits, Dr. Menning recognized a major limitation: poor oral bioavailability and ineffective delivery in traditional skincare formulations.

Determined to overcome these barriers, he developed XDF (transdermal flavosomes)—a novel delivery technology that enables compounds to penetrate the skin barrier and reach their therapeutic targets. This innovation became the foundation of MARK Los Angeles, a brand that combines clinical precision with the power of plant science to deliver real, measurable results.

MARK Los Angeles is driven by the belief that science and nature are most powerful when working together, and that skincare should be both highly effective and expertly formulated.

Products

Lip Rescue Serum
Lip Rescue Serum $18.00
Lip Health Balm
Lip Health Balm $18.00
E.Q. Exfoliating Cleanser
E.Q. Exfoliating Cleanser $48.00
E.Q. Discovery Size Gentle Cleanser
E.Q. Discovery Size Gentle Cleanser $22.00
E.Q. Discovery Size Rescue Serum
E.Q. Discovery Size Rescue Serum $25.00
E.Q. Discovery Size Exfoliating Cleanser
E.Q. Discovery Size Exfoliating Cleanser $22.00
E.Q. Discovery Size Daily Moisturizer
E.Q. Discovery Size Daily Moisturizer $29.00
E.Q. Clear Skin Collectionâ„¢
E.Q. Clear Skin Collectionâ„¢ $302.00
E.Q. Daily Moisturizer
E.Q. Daily Moisturizer $98.00
E.Q. Rescue Serum
E.Q. Rescue Serum $108.00
E.Q. Gentle Cleanser
E.Q. Gentle Cleanser $48.00
E.Q. Discovery Set
E.Q. Discovery Set $88.00

Team Bios

MARK_LA_035.jpg

Mark Menning, PhD

CEO & Co-founder
see bio

Mark Menning, PhD is a pharmaceutical scientist and the founder of MARK Los Angeles, a California-based skincare brand pioneering the use of flavonoids and advanced transdermal delivery to address cold sores, acne, and inflammation. With a PhD in Chemical Engineering and a track record that includes formulating FDA-approved antiviral therapies like Truvada and Atripla, Mark brings a rare blend of clinical expertise and entrepreneurial vision to the beauty and wellness space.

His first venture, Nucleo Life Sciences, provided laboratory services focused on translational pharmaceutics and novel delivery systems, supporting clinical-stage programs for small, mid-sized, and large pharmaceutical companies. At the core of the brand is XDFâ„¢ (Transdermal Flavosomes), a proprietary system designed to solve the long-standing bioavailability issues of flavonoids by enabling them to penetrate the skin effectively.

This technology drives a growing portfolio of performance-first products, including the Lip Rescue Serum and Lip Health Balm—a new standard in cold sore care—as well as the E.Q. Clear Skin collection, a clinically tested line formulated with flavonoids to calm inflammation and visibly improve blemish-prone skin.

Mark is committed to bridging science and skincare, translating plant compounds into clinically validated actives with real-world efficacy and pharmaceutical-grade precision.

Retailers

Amazon

Press

Beauty Independent - Aug 20, 2025 MARK Los Angeles Lip Rescue Serum Nominated for a Beacon Award for Product Innovation "We’re honored to be nominated for Product Innovation – Formula. At MARK Los Angeles, we’ve worked passionately to bring pharmaceutical delivery science into skincare, and this recognition validates the power of our novel XDF delivery system and the untapped potential of flavonoids. The Lip Rescue Serum isn’t just a lip product, it’s a breakthrough for anyone dealing with cold sores and inflammation. If you believe skincare should do more, please vote for us!"
Skincarma Podcast - Jul 07, 2025 The Skincarma Pod Episode 33: Pharma to Flavonoids: Rewriting the Skincare Playbook with Dr. Mark Menning – Pharmaceutical Scientist, Visionary Founder & CEO of MARK Los Angeles "In this episode of the Skincarma Pod, Carmine welcomes Dr. Mark Menning, a pharmaceutical scientist and visionary founder of MARK Los Angeles. They discuss Dr. Menning's unique approach to skincare, which combines pharmaceutical science with a patented and innovative ingredient delivery system. The conversation covers the evolution of antiviral drugs, the under-appreciated power of flavonoids in skincare, and the importance of understanding ingredient penetration for optimizing product efficacy and, ultimately, skin health. Carmine and Mark wonk out on the efficacy of various Vitamin C molecules, the innovative approach of precision-engineered plant-based skincare, and the importance of clinical trials in proving product effectiveness. The dialogue also touches on the crossover between the beauty and pharmaceutical industries, ingredient sourcing and regulatory standards, culminating in Mark's aspirations for the future of the MARK Los Angeles brand."
BeautyMatter - Jun 15, 2025 2025 NEXT50: The Brightest Start-Ups in Beauty "MARK Los Angeles has been named to BeautyMatter’s 2025 NEXT50 list, recognizing the brightest early-stage start-ups shaping the future of beauty. Selected by BeautyMatter’s editorial and intelligence team, the NEXT50 honors innovative brands reimagining how to create, deliver, and scale value in a crowded landscape. MARK Los Angeles was recognized for its breakthrough use of pharmaceutical science and flavonoid delivery to transform skincare and lip health."
BeautyMatter - Jun 10, 2025 Meet The Finalists: BeautyMatter 2025 Awards - Best Breakthrough Wellness (Topicals) MARK Los Angeles - Lip Health "MARK Los Angeles has been nominated for the 2025 BeautyMatter Award in the category of Best Breakthrough Wellness (Topicals). This category honors innovation in topical wellness products, whether through formulation, delivery technology, format, or sustainability. Our nomination recognizes the Lip Health collection, which represents a new approach to treating cold sores using flavonoids and advanced transdermal delivery."
Trend Hunter - May 11, 2025 Plant-Based Clear Skincare Collections "MARK Los Angeles' E.Q. Clear Skin Collectionâ„¢ presents a premium skincare system designed to address multiple complexion concerns through a science-backed, plant-based approach. The four-product regimen combines dermatological research with natural ingredients, featuring a patent-pending XDFâ„¢ delivery system to enhance absorption of key actives like EGCG from green tea and quercetin."

Press Releases

New Launch - Apr 14, 2025 MARK Los Angeles Launches Breakthrough in Cold Sore Care Using Advanced Flavonoid Delivery System
All Press Releases

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